Ctgf migration

Author: clzh

August undefined, 2024

WebConnective tissue growth factor (CTGF), a cystine-knot protein of the CCN family, interacts with a variety of biological response modifiers and participates in several biological … WebJun 1, 2002 · Connective tissue growth factor (CTGF) is a 38-kd protein, originally isolated from supernatants of human vascular endothelial cells, that promotes differentiation, proliferation, and migration of ...

Efficiency of Promoters of Human Genes FAP and CTGF at …

WebOct 29, 2024 · Connective tissue growth factor (CTGF) is a key signaling and regulatory molecule involved in different biological processes, such … WebJun 1, 2006 · Connective tissue growth factor (CTGF) is a member of the CCN [CYR61 (cysteine-rich 61) / CTGF / NOV (nephroblastoma overexpressed)] family of secreted proteins, which are characterized as cysteine-rich matricellular proteins that each contain four modular domains displaying homology to insulin-like growth factor–binding proteins … dasmarinas security bank

New strategy to control cell migration and metastasis regulated by …

WebCTGF promotes the migration of mesenchymal stem cells. A, mixed cell plating assay. HCT116 cells were seeded in 12-well plates at a low confluence and infected with AdCTGF or AdGFP. 15 h after ... WebNov 4, 2016 · CTGF is a matricellular, multifunctional protein that can influence the activity of multiple major signaling pathways, affecting cell adhesion, migration, proliferation, and differentiation. CTGF expression increases after central nervous system (CNS) trauma in rodents, but its function after spinal cord injury has not been elucidated ( 7 – 9 ). WebThe CTGF-mediated increases in κB-luciferase activities were inhibited by RGD, PD98059, U0126 or FAK, and ERK2 mutant. Taken together, our results indicated that CTGF … bite the bullet crossword

The protein-protein interaction between connective tissue growth …

CTGF - an overview ScienceDirect Topics

WebConnective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. WebConnective tissue growth factor (CTGF) is a signaling molecule with several roles in tissue repair and regeneration including promoting cell adhesion, cell migration, cell … dasmarinas schools division officeWebJul 12, 2014 · Connective tissue growth factor (CTGF)/CCN family member 2 (CCN2) is a CCN family member of matricellular signaling modulators. It has been shown that … dasmarinas science high school

"WebDec 12, 2024 · Angiogenesis is the main basis of the proliferative phase of wound healing, cell proliferation, migration, and differentiation. The integrity of the endothelial cell structure plays a very important role in maintaining normal blood circulation in the body. ... Connective tissue growth factor (CTGF) is a matricellular protein from the … " - Ctgf migration

Ctgf migration

Invasion ability of Panc-1 cells by transwell chamber assay. (A ...

WebJun 6, 2012 · These tumors demonstrate several phenotypes potentially related to CTGF function namely: cell migration, absent tumor cell apoptosis, as well as, reactive and well vascularised myofibroblast rich stroma and fibrosis development locally and in distal organs. ... Key roles for connective tissue growth factor (CTGF/CCN2) are demonstrated in the ... WebJul 1, 2024 · Intriguingly, the effect of CTGF on cell migration can either be positive or negative in a cell-type-specific manner [23,24]. The differential actions of CTGF may be attributed to different interacting partners in the extracellular domain . ... Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells ...

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WebCTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, …

WebJul 12, 2014 · Connective tissue growth factor (CTGF)/CCN family member 2 (CCN2) is a CCN family member of matricellular signaling modulators. It has been shown that … WebApr 13, 2024 · The identification of tissue-specific promoters for gene therapeutic constructs is one of the aims of complex tumor therapy. The genes encoding the fibroblast activation protein (FAP) and the connective tissue growth factor (CTGF) can function in tumor-associated stromal cells but are practically inactive in normal adult cells. Accordingly, the …

WebApr 11, 2024 · During chronic hepatitis B virus (HBV) infection, hepatic fibrosis is a serious pathological condition caused by virus-induced liver damage. The activation of hepatic stellate cells (HSCs) is a central event in the occurrence and progression of liver fibrosis. Although accumulating evidence has shown that HBV directly stimulates HSC activation, … WebOct 6, 2024 · Apart from inhibiting TNBC cell migration via CTGF, ATL-1 downregulated the expression of CTGF in fibroblasts and decreased the ability of breast cancer cells to transform fibroblasts into cancer-associated fibroblasts (CAFs), which in turn increased the sensitivity of TNBC cells to paclitaxel. In a mouse model, we found that ATL-1 treatments ...

WebCTGF can regulate the activity of diverse growth factors or integrins. 19,20 CTGF was found to activate the cellular proliferation, migration, and fibrogenesis. 21 CTGF has also been proven to participate in certain types of cancers of drug-resistance.

WebAs shown in Fig. 5, the number of Panc-1 cells that invaded through the matrigel chamber was signi fi cantly less in the group transfected with MUC1 siRNA than that observed in control groups (P b ... bite the bullet civil warWebConnective tissue growth factor (CTGF) is a signaling molecule with several roles in tissue repair and regeneration including promoting cell adhesion, cell migration, cell proliferation and angiogenesis. ... Results of the in vitro scratch assay shows that the membranes containing CTGF promoted cell migration and supported fast in vitro wound ... da smartschoolWebOct 26, 2024 · Connective tissue growth factor (CTGF), also known as CCN family protein 2 (CCN2), is composed of four domains, including insulin-like growth factor binding … bite the bullet and crack the nutsWebFeb 6, 2024 · The migration assays showed that GFs with CM from CAFs strongly enhanced GIST-T1 cell migration compared to GF only, while the effect was markedly decreased by anti-TGF-β1 blocking antibody (Fig ... dasmarinas vaccination scheduleWebJul 18, 2024 · This analysis also revealed several other up-regulated genes such as A2m and Nfkbiz as members of Il-6, Cxcl1, Ctgf, and Tgfb2 interactome . Future experimental studies may validate the potential role up-regulation of Il-6, Cxcl1, Ctgf, and Tgfb2 may have in promoting cancer cell migration, invasion, and cancer-induced bone metabolism. dasmarinas wether forecastWebJun 3, 2013 · To examine the effect of CTGF on cell migration, stably shRNA-CTGF-expressing 1024 and 1047 6–10B NPC cells were cultured on transwell apparatus. ... Li … dasma technical data sheetWebIn the former study, we discovered that the expression of adiponectin was obviously decreased in keloid tissues compared with those in normal controls, furthermore, adiponectin inhibited CTGF-mediated KFs proliferation, migration and the over-accumulation of ECM. 13 But the correlation between adiponectin and inflammatory … bite the bullet cast and crew